Publications‎ > ‎

Health function

1. Yamada H, Oshiro E, Kikuchi S, Hakozaki M, TakahashiH, Kimura KI. (2014) Hydroxyeicosapentaenoic acids from the Pacific krill show high ligand activities for PPARs. Journal of Lipid Research 55:895-904.

2. Yamada H, Kikuchi S, Inui T, Takahashi H, Kimura KI. (2014) Gentiolactone, a secoiridoid dilactone from Gentiana triflora, inhibits TNF-a, iNOS and Cox-2 mRNA expression and blocks NF-κB promoter activity in murine macrophages. PLoS ONE 9(11):e113834

3. 山田秀俊 (2014) イサダ由来の8-ヒドロキシエイコサペンタエン酸(8-HEPE)による脂肪燃焼促進作用 New Food Industry 56(9): 29-34

4.  山田秀俊 (2014) イサダ(ツノナシオキアミ)由来の新たな抗肥満成分8-HEPE BIO INDUSTRY 31(12):46-5

1. Yano A, Abe A, Aizawa F, Yamada H, Minami K, Matsui M, Kishi M (2013) The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home. Marine Drugs 11: 4993-5007


1. Sadzuka Y, Sugiyama I, Miyashita M, Ueda T, Kikuchi S, Oshiro E, Yano A, Yamada H. (2012) Beneficial effects by intake of Euphausiacea pacifica on high-fat diet-induced obesity. Biol. Pharm. Bull. 35:568-572

2. Yano A, Kikuchi S, Takahashi T, Kohama K, Yoshida Y. (2012) Inhibitory effects of the phenolic fraction from the pomace of Vitis coignetiae on biofilm formation by Streptococcus mutans. Arch. Oral Biol. 57:711-719

3. Yano A, Konno N, Imai S, Kato H. (2012) Inhibitory effects of polysaccharides on the cariogenic activities of Streptococcus mutans. Biosci. Biotechnol. Biochem. 76:2313-2316


1. Yamada H, Ueda T, Yano A. (2011) Water-Soluble Extract of Pacific Krill Prevents Triglyceride Accumulation in Adipocytes by Suppressing PPARγ and C/EBPα Expression. PLoS ONE. 6: e21952

2. Kimata K, Yamaguchi M, Saito Y, Hata H, Miyake K, Yamane T, Nakagawa Y, Yano A, Ito K, and Kawarasaki Y. (2011) High cell-density expression system: A novel method for extracellular production of "difficult-to-express" proteins. J Biosci Bioeng. 113(2):154-9


1. Sasaki-Imamura T, Yano A, Yoshida Y. (2010) Production of indol from L-tryptophan and effects of these compounds on biofilm formation by Fusobacterium nucleatum ATCC25586. Applied and Environmental Microbiology 76:4260-4268

2. Nakade K, Nakagawa Y, Yano A, Sato T, Sakamoto Y. (2010) Characterization of an extracellular laccase, PbLac1, purified from Polyporus brumalisFungal Biology 114:609-618

3. Nakagawa Y, Sakamoto Y, Kikuchi S, Sato T, Yano A. (2010) A chimeric laccase with hybrid properties of the parental Lentinula edodes laccases. Microbiological Research. 165:392-401

4. Nakagawa Y, Kikuchi S, Sakamoto Y, Yano A. (2010) Identification and characterization of CcCTR1, a copper uptake transporter-like gene, in Coprinopsis cinereaMicrobiological Research. 165:276-287 

5. Yano A, Kikuchi S, Yamashita Y, Sakamoto Y, Nakagawa Y, Yoshida Y. (2010) The inhibitory effects of mushroom extracts on sucrose-dependent oral biofilm formation. Appl. Microbiol. Biotechnol. 86(2):615-623


1. Yano A, Kikuchi S, Nakagawa Y, Sakamoto Y, Sato T. (2009) Secretory expression of the non-secretory-type Lentinula edodes laccase by Aspergillus oryzaeMicrobiolgical Research. 164:642-649


1. Sakamoto Y, Keiko N, Yano A, Nakagawa Y, Hirano T, Irie T, Watanabe H, Nagai M, Sato T. (2008) Heterologous expression of lcc1 from Lentinula edodes in tobacco BY-2 cells results in the production an active, secreted form of fungal laccase. Appl. Microbiol. Biotechnol. 79:971-980